2019 was my first year, which was also the 20th anniversary celebration.
Venue: Huge, beautiful convention center. It was a little overwhelming but handled the crowds well. I had plenty of space behind my booth and load in/out went very smoothly. Had lots of food options in the con, too (though naturally pricey).
Staff: Helpful and friendly! Everyone knew where everything was when asked (which is pretty impressive with a venue this size). I didn't run into any problems personally.
Layout: Not the best layout for artists due in part to the sheer number of artists and exhibits. I got a lucky spot near the dealers area, but others along the back wall seemed a bit slower from what I could see.
Attendance: REALLY HIGH - like 60,000 easily, it's massive.
Affordability: Kansas City is pretty cheap if you know what you're doing, but as a comic con the table price is high. Plus- attendees were more keen on spending money on dealers goods and autographs than artists, in general. Lots of folks looking for smaller, cheaper goods, not prints or big purchases. Can't say it's worth traveling too far to.
Conclusion: A very pop-culture oriented comic con with lots of celebs. HUGE venue with LOTS of artists and vendors so it was easy to get literally lost in the crowd. Sales did not reflect the ludicrous amount of people present (or hefty table price), but attendees were pretty open to hearing about indie projects which was nice. Still, for artists: I'd travel from out of state only if you can cut costs a LOT one way or another.